Ultrasonic Vascular Stent Spraying
Vascular stent refers to the expansion of the shape of the lumen balloon, placed in the lesion within the stent in order to support the narrow occlusion of blood vessels, reduce vascular elastic retraction and reshaping, to maintain lumen blood flow purposes.
CHEERSONIC Ultrasonic Atomizing Spraying Equipment is a high-precision ultrasonic atomizing spraying system specially designed for the surface treatment of micro instruments. It is dedicated to the combination of ultrasonic atomizing spraying technology and coating preparation of vascular scaffolds to guide the process development and optimize the coating quality purpose. CHEERSONIC ultrasound in accordance with the physical mathematical modeling, fluid dynamics simulation, experimental detection and analysis, process development and application of the route to study and eventually successfully developed for vascular stent ultrasonic medical spraying equipment.
CHEERSONIC ultrasonic optimization of the process parameters and found that ultrasonic frequency of this parameter is the main factor affecting the quality of the coating. Based on the optimized parameters, we constantly improve the ultrasonic frequency to achieve the change of ultrasonic atomizing spray to ultrasonic medical spraying. The experiment of the preparation of the stent coating verifies that the ultrasonic medical spraying equipment completely eliminates common thick edges, bridges, bumps and particles Equal issues. The surface roughness decreased from 6.35nm before optimization to 1.72nm, the coating quality was significantly improved. In addition, the incremental coating test results showed that the coating quality deviation of multiple spray coating was about 10μg in the same stent, and the optimized process had good reliability Sexual and stability.
The commonly used stent coating technology can be ultrasonic coating, which sprays polymer and drug solutions (using various solvents) onto the stent, so that a uniform drug release layer can be uniformly deposited on the surface of the stent. Ultrasonic nozzles have the advantage of penetrating complex stent geometries, ensuring complete coverage of all pillar surfaces without the need for webbing. The soft atomized spray can adhere well to the surface, and the morphological characteristics of the coating can be adjusted by modifying the process parameters. The advantage of the ultrasonic spraying system is that the coating formed by dip coating is much thinner, can save spraying materials to a large extent, and the nozzle is not easy to be blocked.
UAM3000 is a high-performance stent spraying equipment developed for stent series products, mainly used for drug coating on the surface of stents. The special nozzle for ultrasonic stent with national patent can realize accurate application of medicine, and the fixture specially equipped for stent is convenient for loading and unloading. This device has the characteristics of supporting multiple series and multiple types of stents, high drug utilization, accurate drug delivery, and high uniformity of the stent membrane layer.
Video of Precision Ultrasonic Stent Coating Machine
