Stenotic and Dilatable Drug-coated Intracranial Stents
Stenotic and Dilatable Drug-coated Intracranial Stents – Stent Coating – Cheersonic
Intracranial atherosclerotic disease remains the most common cause of ischemic stroke and one of the leading causes of ischemic stroke in Asian populations. Intracranial atherosclerotic disease has a high disability and mortality rate, and even intensive drug treatment may lead to vascular stroke or cerebrovascular death.
Endovascular treatment of intracranial atherosclerotic disease Intracranial stenting is an effective method for the treatment of patients with symptomatic intracranial atherosclerotic stenosis, which can effectively improve brain tissue perfusion in the distribution area of the responsible artery, thereby reducing stroke Risk of recurrence, improved neurological outcome.
After receiving intracranial artery stenting, there is still a high rate of stroke recurrence. According to reports, the incidence of in-stent restenosis 6 months after intracranial artery stenting is as high as 29.7%, which is significantly higher than that of carotid artery stenting, and is similar to that of coronary artery bare metal stents. quite. In-stent restenosis may be the result of a combination of factors, among which vascular smooth muscle cell proliferation and migration leading to vascular intimal hyperplasia play an important role.
Drug-coated stents may be superior to bare metal stents in the treatment of intracranial atherosclerotic diseases. The drug-loaded layer contains anti-cell proliferation drugs such as rapamycin, which can inhibit the proliferation and migration of vascular smooth muscle cells, thereby preventing regeneration in the stent. narrow. Domestic cerebrovascular drug-eluting stents are mostly balloon-expandable rapid-exchange stent systems.
It is expected that the application of drug-eluting stents in intracranial atherosclerotic diseases can solve the clinical problem of in-stent restenosis to a certain extent.
Cheersonic provides a variety of ultrasonic coating equipment and solutions for manufacturing industry of implantable, in interventional medical devices, the drug-eluting stents and balloon catheters. Our ultrasonic coating systems have been used to spray anti-restenosis drug eluting polymer solutions onto implantable stents. Compared to conventional two-fluid nozzles, ultrasonic nozzles can spray a more uniform drug coating that completely covers the stent without the orange peel and adhesion to a complex stent. And the coatings are much thinner than can be achieved with dip coating, saving spray material.
- Ideal for R&D and low-volume production
- Compact desktop design that is easy to move
- The material usage ratio > 95%
- Reliable, repeatable and consistent coating, uniformity of ±5%
- Max. length 100mm, max. diameter 60mm
About Cheersonic
Cheersonic is the leading developer and manufacturer of ultrasonic coating systems for applying precise, thin film coatings to protect, strengthen or smooth surfaces on parts and components for the microelectronics/electronics, alternative energy, medical and industrial markets, including specialized glass applications in construction and automotive.
Our coating solutions are environmentally-friendly, efficient and highly reliable, and enable dramatic reductions in overspray, savings in raw material, water and energy usage and provide improved process repeatability, transfer efficiency, high uniformity and reduced emissions.
Chinese Website: Cheersonic Provides Professional Coating Solutions
