Drug Balloon Spraying Equipment

1. Equipment precision requirements

Nozzle design: For this kind of drug balloon spraying equipment with a large range of diameters and lengths, the design of the nozzle is crucial. The nozzle needs to be able to accurately spray according to the different diameters and lengths of the balloon. For small diameter (2.0mm) balloons, the nozzle should have a fine spray function to ensure that the drug can be evenly sprayed on the balloon surface to avoid drug accumulation or uneven spraying. For large diameter (12mm) and long length (300mm) balloons, the spray angle and spray range of the nozzle should be able to be properly adjusted to ensure that the drug can cover the entire balloon surface.

Flow control: The equipment needs to accurately control the flow rate of drug spraying. Balloons of different diameters and lengths have different requirements for the amount of drug. For example, large diameter and long balloons may require more drugs to ensure sufficient drug concentration and coverage area. The flow control system should be able to dynamically adjust according to the size of the balloon to ensure that the amount of drug sprayed each time is accurate, while also considering the utilization rate of the drug to avoid waste.

2. Challenges and responses to coating uniformity

Impact of changes in balloon shape and size: Due to the wide range of changes in balloon diameter and length, ensuring coating uniformity is a key challenge. The curvature of the balloon varies greatly at different diameters. Small-diameter balloons have large curvatures, making it relatively difficult for drugs to adhere to and distribute on the surface; while large-diameter balloons have small curvatures, but it is not easy to ensure uniformity in the long axis direction. During the spraying process, the equipment needs to be able to dynamically adjust the spraying parameters according to the shape and size of the balloon, such as the rotation speed of the nozzle, the rotation and movement speed of the balloon, etc.

Response strategy: A multi-axis linkage spraying method can be used. For example, let the balloon move along the axial direction while rotating, and the nozzle also moves in a circle around the balloon, and adjusts the movement speed and spray angle in real time according to the size of the balloon. This complex movement method ensures that the drug is evenly distributed on the entire balloon surface. At the same time, during the spraying process, the optical detection system can be used to monitor the uniformity of the coating in real time, and once unevenness is found, the spraying parameters can be adjusted in time.

3. Drug applicability and compatibility

Consideration of drug properties: Different drugs have different physical and chemical properties, such as viscosity, solubility, stability, etc. For such a wide range of balloon sizes, the equipment needs to consider the applicability of the drug. For example, a drug with high viscosity may require a higher spraying pressure to atomize well, but too high a pressure may damage the balloon, especially a small diameter balloon. The equipment should be able to adjust the pressure according to the viscosity and other characteristics of the drug.

Compatibility with balloon materials: Balloons are usually made of special medical materials, and the drug may interact with the balloon material during the spraying process. The equipment needs to ensure that this interaction does not affect the performance of the drug and the quality of the balloon. For example, some drugs may corrode or swell the balloon material. The equipment should avoid this during design and operation. It may be necessary to pretreat the balloon or select a suitable drug solvent.

4. Versatility and adjustability of the equipment

Modular design: In order to adapt to the spraying of balloons of different diameters and lengths, the equipment can adopt a modular design. For example, the nozzle module can be quickly replaced according to the size of the balloon, and different nozzle modules have the best spray parameter settings for balloons of a specific size range. At the same time, the control system of the equipment should be highly adjustable, and can easily input the size parameters of the balloon and automatically adjust other related spraying parameters, such as movement speed, flow rate, pressure, etc.

Automation and software control: Equipment with a high degree of automation is more suitable for such complex spraying tasks. Through software control, the spraying program of balloons of different sizes can be pre-set. The operator only needs to enter basic information such as the size and drug type of the balloon, and the equipment can automatically complete the spraying process. In addition, the software can record the parameters and effects of each spraying, which is convenient for subsequent quality traceability and process optimization.

About Cheersonic

Cheersonic is the leading developer and manufacturer of ultrasonic coating systems for applying precise, thin film coatings to protect, strengthen or smooth surfaces on parts and components for the microelectronics/electronics, alternative energy, medical and industrial markets, including specialized glass applications in construction and automotive.

Our coating solutions are environmentally-friendly, efficient and highly reliable, and enable dramatic reductions in overspray, savings in raw material, water and energy usage and provide improved process repeatability, transfer efficiency, high uniformity and reduced emissions.

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