Commercial Cardiac Occluder
Commercial Cardiac Occluder – Biomedical Ultrasonic Spray Coating – Cheersonic
Congenital heart disease mainly refers to heart defects caused by abnormal heart development in newborns or children. Among all kinds of congenital heart disease, cavity wall or vascular wall defect is the most common structural heart defect, and its incidence in neonates is close to 1%, with 1.4 million new cases worldwide every year. Common types of congenital heart disease include ventricular septal defect, atrial septal defect, patent ductus arteriosus, and patent foramen ovale, among others. Transcatheter cardiac occluders do not require open-heart surgery and are the most effective way to treat these structural heart defects.
The current commercial cardiac occluder is composed of a non-degradable nickel-titanium alloy mesh and a polymer blocking membrane. After implantation, the metal material remains permanently in the heart, which may increase the risk of long-term complications, such as endothelial Delayed metabolism, thrombosis, wear and perforation, and even fatal late atrioventricular block. Biodegradable occluder is the best solution to such problems. It can be used as a temporary skeleton to guide the regeneration of cardiac tissue, and after the defect is replaced by new tissue, it is gradually absorbed by human tissue, and finally restores cardiac function reconstruction.
The ultrasonic drug-eluting stent spray coating system can be applied to the preparation of polymer coating for preventing vascular restenosis on the surface of implantable drug-eluting stent. Compared to conventional two-fluid nozzles, ultrasonic nozzles can spray a more uniform drug coating that completely covers the stent without the orange peel and adhesion to a complex stent. The soft atomized spray adheres well to surfaces and coating morphology characteristics can be adjusted by modifying process parameters. In addition, the stent coating obtained by ultrasonic spray coating technology is thinner than dip-coating. Ultrasonic spray coating technology can precisely control the amount of drug sprayed on the stent, making the control of the spraying more precisely.
The special nozzle for ultrasonic stent with national patent can realize accurate application of medicine, and the fixture specially equipped for stent is convenient for loading and unloading. This device has the characteristics of supporting multiple series and multiple types of stents, high drug utilization, accurate drug delivery, and high uniformity of the stent membrane layer.
