Ultrasonic Medical Stent Coating
The stent was implanted to dilate the atherosclerotic, plaque-stenotic arteries and to restenate the coronary vessels following myocardial infarction. However, in up to 20% of patients, regrowth of blood vessel inner wall cells or incomplete healing of the endothelial cell lining in the lumen of blood vessels can still cause recurrent clogged arteries, which is called restenosis.
The introduction of stent technology demonstrates excellent performance in preventing occlusion and restenosis. With the introduction and development of drug-eluting chemicals, stents have revolutionized the treatment of coronary artery disease by reducing stent restenosis and the need for target vessel revascularization. However, with the dramatic increase in the use of some drug-eluting chemicals, stent thrombosis has become an important concern. The formation of restenosis and thrombosis is the result of a combination of factors. The ideal stent coating for drug carrier materials and drug formulations not only inhibits thrombus formation, inflammatory response, and proliferation of smooth muscle cells, but also facilitates the process of reendothelialization.
The CHEERSONIC Ultrasonic Atomizing Nozzle generates very fine droplets and achieves a uniform controlled coating on medical and other sensitive or small devices. The nozzle jet speed is low and can therefore be used to apply a thin layer of valuable chemicals with minimal overspray. Ultrasonic nozzles provide some key advantages in stent coating and other precision medical device coatings. Ultrasonic nozzles also provide excellent repeatability in spray speed and droplet size, while reducing the amount of paint consumed.
The commonly used stent coating technology can be ultrasonic coating, which sprays polymer and drug solutions (using various solvents) onto the stent, so that a uniform drug release layer can be uniformly deposited on the surface of the stent. Ultrasonic nozzles have the advantage of penetrating complex stent geometries, ensuring complete coverage of all pillar surfaces without the need for webbing. The soft atomized spray can adhere well to the surface, and the morphological characteristics of the coating can be adjusted by modifying the process parameters. The advantage of the ultrasonic spraying system is that the coating formed by dip coating is much thinner, can save spraying materials to a large extent, and the nozzle is not easy to be blocked.
UAM3000 is a high-performance stent spraying equipment developed for stent series products, mainly used for drug coating on the surface of stents. The special nozzle for ultrasonic stent with national patent can realize accurate application of medicine, and the fixture specially equipped for stent is convenient for loading and unloading. This device has the characteristics of supporting multiple series and multiple types of stents, high drug utilization, accurate drug delivery, and high uniformity of the stent membrane layer.
Video of Precision Ultrasonic Stent Coating Machine
